Course Description:

This online course is worth 2 CE.

When it comes to the safety and efficacy of sedation, three of the most important subjects arguably include pharmacology, patient selection, and airway management. All three are tied intimately to patient safety, and pharmacology also has a great deal to do with sedation effectiveness.

Understanding the mechanisms of how drugs act, and how the body responds to their action are key to their safe and effective use.

Dr. Anthony Feck plunges into his favorite topic to share with you pharmacokinetics and pharmacodynamics of a wide range of sedative agents. You learn why and how they work; why some are better than others; and the methods used to reverse the effects of each.


  • Understand the pharmacokinetics of common IV drugs, including potency, efficacy, and plasma-protein binding
  • Recognize the role and phases of metabolism, induction, and inhibition of CYP3A4
  • Identify polymorphism, gross anatomy, and excretion
  • Learn the pharmacodynamics that effects sedation
  • Recognize agonists and antagonists
  • Understand the role of the GABA receptor
  • Discover benzodiazepines and their mechanism of cation, abuse, and tolerance, withdrawal, and risk factors.
  • Identify various benzodiazepines and key points about each
  • Recognize the critical reversal agent and protocols for use
  • Discuss the pharmacokinetics and pharmacodynamics of opioids including side effects and agonist agents
  • Learn about the less-commonly-used sedatives and their effects on organ systems
  • Discover the pharmacology behind nitrous oxide

Purchase of this course grants access for one year and requires an internet connection, computer with video and audio capabilities, and in some cases, Adobe Reader to view handouts and articles. 

Watch the video and complete the quiz to earn 2 CE credits.

Scientific support and additional resources are available here. 

You can download this course and watch it anywhere using the DOCS APP. Get it on Google Play or the Apple Store.

This course requires an active sedation permit or previous attendance at Master Series – Advanced Sedation, IV Sedation Certification or IV Sedation Recertification.

340 Anesthesia and Pain Management: 2.0 hours

Original release date: 10/5/2020

DOCS online courses are available to the purchaser for one year from date of purchase.
No refund of course tuition is available.




Dr. Anthony Feck

How can I meet my state’s requirements?

To learn more about how DOCS Education’s full range of courses can satisfy your state’s regulatory requirements, visit This unique online resource is kept up-to-date with the latest in sedation legislation by DOCS Education’s fulltime regulatory counsel. Contact one of our course advisers with any questions or visit our course listings to see upcoming classes and locations.

DOCS Education courses carry the AGD PACE certification

DOCS Education is the nation’s premier provider of safe sedation and advanced dentistry education, having trained almost 24,000 dentists. Since 2000, our courses have been accepted by the AGD for Fellowship/Mastership and membership maintenance credit. We offer extensive CE opportunities, both in-person and online, that meet your needs.

What is DOCS Education?

DOCS Education is an exclusive community of professionals serving at the forefront of dentistry. We offer world-class courses on safe sedation and advanced dentistry, relying on instructors who are consistently ranked among the very best in the nation. We also are a supportive network of members who guide one another to be better, more confident, more successful dentists.